Paediatric Respiratory Medicine
An Introduction to Paediatrics
A number of respiratory conditions largely affect the paediatric patient, including cystic fibrosis, asthma and allergy. Recent research into genetic drivers has revolutionized the treatment of cystic fibrosis, with new and effective targeted therapies available and undergoing further research. In asthma, treatments such as inhaled corticosteroids are well established, but research into innovative therapies is ongoing.
Browse our selection of video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and a selection of peer-reviewed articles from the journal portfolio.
Paediatric Respiratory Medicine Content
Contemporary insights on the management of sickle cell disease: Focus on complications and recent advances in therapy
Three experts discuss the management of complications of sickle cell disease, as well as recent advances in therapy.
- Summarize the various manifestations and multiple complications of SCD
- Appraise the practical considerations for the multidisciplinary management of SCD complications
- Interpret the clinical data for established and recently approved therapies for SCD and apply them to clinical practice
Theresa W Guilbert, AAAAI 2023: The VOYAGE study: Impact of exacerbation history on dupilumab efficacy in children with asthma
Dupilumab is indicated as an add-on maintenance treatment in children aged 6 years and older with asthma, and demonstrated clinical efficacy in the pivotal VOYAGE study (NCT0294895). We caught up with Dr Theresa W Guilbert (Cincinnati Children’s Hospital & Medical Center; University of Cincinnati, Cincinnati, OH, USA) to discuss the main findings from a post-hoc […]
Theresa W Guilbert, AAAAI 2023: Health and economic burden of asthma exacerbations in children
touchRESPIRATORY were delighted to speak with Dr Theresa W Guilbert (Cincinnati Children’s Hospital & Medical Center; University of Cincinnati, Cincinnati, OH, USA) about the health and economic burden of asthma exacerbations in children, and the limitations of current therapeutic options for children with asthma. The abstract ‘Impact Of Exacerbation History On Dupilumab Efficacy In Children […]
Management of severe paediatric asthma: From hospital to home
Members of the MDT and a patient advocate discuss the optimal management of severe asthma in children
- Recall the diagnostic workup for severe type 2 asthma in children
- Explain the pathophysiology of severe type 2 asthma and how this can guide treatment decisions
- Discuss the importance of the MDT in optimizing the management of children with severe asthma
Robin Deterding, ERS 2022: Findings from the InPedILD Trial
The InPedILD trial was a phase 3, double-blind placebo-controlled trial investigating nintedanib in children and adolescents with fibrosing interstitial lung diseases (ClinicalTrials.gov: NCT04093024). We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) to discuss the aims, design, eligibility criteria and findings from the phase 3 study. […]
Robin Deterding, ERS 2022: Nintedanib for Children and Adolescents with Fibrosing Interstitial Lung Diseases
Nintedanib is an inhibitor of tyrosine kinases involved in the progression of pulmonary fibrosis and blocks the signalling pathways involved in fibrotic processes. We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) around the incidence, prognosis and unmet needs in the treatment of childhood interstitial lung […]
Identifying, diagnosing and treating patients with later-onset SMA
Dr Julie Parsons reviews the diagnosis and approved treatments for later-onset SMA, highlighting their impact on the natural history of SMA.
- Recall possible symptoms of SMA in adolescent and adult patients and relevant differential diagnostic tests
- Appraise the role of current and future treatment approaches for improving outcomes in patients with older-onset SMA
- Evaluate how the natural history of SMA is evolving with the use of disease-modifying therapies
Maintaining quality of life in patients with later-onset SMA: The patient journey from diagnosis to management
Watch members of the MDT and two patients discuss the diagnosis and management of SMA in adolescents and adults.
- Recall the typical clinical presentation of patients with milder SMA phenotypes and the processes for differential diagnosis
- Discuss patient needs as they transition from paediatric to adult healthcare services
- Formulate processes for the provision of multidisciplinary care to adolescent and adult patients with SMA
Nirsevimab: An Extended Half-life Monoclonal Antibody for the Prevention of Infant Respiratory Syncytial Virus Infection
touchREVIEWS in Respiratory & Pulmonary Medicine. 2021;6(1):38–41 DOI: https://doi.org/10.17925/USPRD.2021.6.1.38
Respiratory syncytial virus (RSV) is a ubiquitous virus that causes annual epidemics of infection in young children in all parts of the world. In temperate regions, epidemics are seasonal, and predictable during the winter months. Approximately half of all infants develop their first RSV infection prior to their first birthday. By 24 months of age, […]
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