Mepolizumab is a humanized monoclonal antibody used to treat severe eosinophilic asthma. We caught up with Dr Ronald Strauss (Case Western Reserve University; Cleveland Allergy and Asthma Center, Cleveland, OH, USA), a valued member of our Editorial Board for touchREVIEWS in Respiratory & Pulmonary Diseases, to discuss the rationale, findings and clinical significance of his […]

We caught up with Dr Giselle Mosnaim (NorthShore University HealthSystem, Evanston, IL, USA; University of Chicago Pritzker School of Medicine, Chicago, IL, USA) around the current therapeutic options for asthma and their limitations, and what is known about the clinical utility of digital inhalers in the treatment of asthma. The abstract ‘Relationship between medication adherence […]

Dupilumab is indicated as an add-on maintenance treatment in children aged 6 years and older with asthma, and demonstrated clinical efficacy in the pivotal VOYAGE study (NCT0294895). We caught up with Dr Theresa W Guilbert (Cincinnati Children’s Hospital & Medical Center; University of Cincinnati, Cincinnati, OH, USA) to discuss the main findings from a post-hoc […]

Night-time awakenings greatly affect the wellbeing of patients with severe asthma and challenges persist in its long-term treatment. touchRESPIRATORY were delighted to speak with Dr Warner Carr (Allergy & Asthma Associates of Southern California, A Medical Group; Southern California Research, Mission Viejo, CA, USA) about the impact of night-time awakenings and treatment challenges in patients […]

For over four decades, polls in the USA have demonstrated that nearly 70% of smokers want to quit and 55% of smokers have attempted to quit in the past year.1 Over these decades, despite advances in medications and behavioural treatments, less than 10% of smokers successfully quit.2 Sadly, an estimated 31 million adult Americans continue to smoke and 11 million are e-cigarette users.3,4 […]

Obstructive sleep apnoea (OSA) is a widespread disorder that affects millions of individuals worldwide.1 It is characterized by repeated episodes of upper airway obstruction during sleep; these episodes can have several negative consequences, including daytime sleepiness, impaired quality of life and an increased risk of developing other health problems, such as hypertension, heart disease and stroke.2 To effectively diagnose and treat OSA, it is essential […]

Asthma is a common and heterogeneous disease affecting approximately 10% of the population.1 Severe asthma – a subset of the disease that affects a fraction of patients with asthma but comprises more than half of the morbidity, mortality and costs relating to asthma – is predominantly caused by smouldering type-2 eosinophilic airway inflammation.2,3 Until now, the main strategy […]

Lung cancer remains the leading cause of cancer-related death.1 However, five-year survival in lung cancer varies greatly based on the stage of the disease at diagnosis.2 Early lung cancer diagnosis through screening with low-dose computed tomography (CT) demonstrated a 20% reduction in lung cancer mortality in current or former smokers with a history of 30 or more […]