An Introduction to Allergic Diseases
The incidence of respiratory allergies is increasing, particularly in industrialized areas. Allergic inflammation can occur in both the upper and lower airways, and can differ substantially in intensity. Traditional drug therapy such as antihistamines, corticosteroids, anticholinergic agents and leukotriene inhibitors is important in reducing and preventing symptoms and is essential in acute use. More recent therapies including anti-immunoglobin E (IgE) therapy, anti-interleukin (IL) monoclonal antibodies, and phosphodiesterase 4/phospholipaseA2 inhibitors, have improved outcomes. However, in order to develop more effective therapies, further research is needed into the molecular mechanisms underlying respiratory allergy onset, particularly in terms of intracellular reactions and the cytosolic Ca2+ balance.
Browse our selection of video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and a selection of peer-reviewed articles from the journal portfolio.
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David Fleischer: Updates in Peanut Allergy Treatment
TouchRESPIRATORY got the opportunity to catch up with Dr. David Fleischer (Children’s Hospital Colorado, Aurora, CO, USA) to discuss the current available therapies and future of the treatment paradigm for peanut allergy. Questions How has the approval of Palforzia impacted the treatment paradigm for peanut allergies? (0:14) What questions remain unanswered regarding oral immunotherapies and […]
Frédéric de Blay, EAACI 2021: Anti-Fel D 1 Monoclonal Antibodies Reduce the Rate of Early Asthma Responses
touchRESPIRATORY joins Professor Frédéric de Blay (University Hospital of Strasbourg, Strasbourg, France) at EAACI 2021 to discuss the results of a phase 2, randomised, double-blind, placebo-controlled study of anti-Fel d 1 monoclonal antibodies in reducing the rate of early asthma responses, chest symptoms and rescue medication use in cat-allergic subjects with mild asthma for up […]
Dermot Ryan, IPCRG 2021: Allergen Immunotherapy in Primary Care
TouchRESPIRATORY got the opportunity to catch up with Dr Dermot Ryan (Asthma UK Centre for Applied Research, The University of Edinburgh, Edinburgh, Scotland) around his presentation on ‘Respiratory Allergy: The Role of Immunotherapy in Primary Care.’ which was presented at The IPCRG 10th World Conference, 6-8 May, 2021. Questions According to current IPCRG guidelines, for which […]
COVID-19 Pandemic—Allergen-specific Immunotherapy Positioning in Respiratory Allergy
US Respiratory & Pulmonary Diseases. 2020;5(1):10-1 DOI: https://doi.org/10.17925/USPRD.2020.5.1.10
Globally, the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected in excess of 55 million people and is associated with over 1.3 million deaths to date (European Centre for Disease Prevention and Control data).1 COVID-19 is placing significant strain on all aspects of routine healthcare and has raised […]
Dupilumab—A Potential New Biologic for Chronic Rhinosinusitis with Nasal Polyps
US Respiratory & Pulmonary Diseases. 2020;5(1):15-7 DOI: https://doi.org/10.17925/USPRD.2020.5.1.15
Chronic rhinosinusitis (CRS) is a clinical syndrome defined by symptomatic inflammation of the paranasal sinuses and nasal cavity for at least 12 weeks in duration. Historically, CRS has been classified into 2 subgroups, CRS with nasal polyps (CRSwNP) and CRS without nasal polyps. Those with CRSwNP have a more significant burden of disease and poor […]
COVID-19, Asthma and Allergies — What We Know So Far
A new coronavirus (SARS-CoV-2) infection began to disseminate in Wuhan, China in early December 2019 and has rapidly spread to almost every country around the globe, with the number of confirmed cases increasing every day. The disease condition associated with this novel coronavirus is referred as coronavirus disease (or COVID-19), and this outbreak was declared […]
Call for Submissions 2018
US Respiratory & Pulmonary Diseases, 2017;2(1):Epub ahead of print
US Respiratory & Pulmonary Diseases invites colleagues in the respiratory care and pulmonary disease community to contribute articles for the 2018 edition. US Respiratory & Pulmonary Diseases aims to provide practicing physicians, and related healthcare professionals in the field, with concise and timely articles that provide practical advice and help them in their day-to-day clinical […]
Sublingual Immunotherapy for Respiratory Allergy
European Respiratory and Pulmonary Diseases, 2015;1(1):25–6 DOI: //doi.org/10.17925/ERPD.2015.01.01.25
In the late 1980s, sublingual allergen immunotherapy (SLIT) was proposed as an ‘alternative’ to subcutaneous allergen immunotherapy (SCIT).1,2 The main aim was to reduce systemic reactions and the risk of anaphylaxis, which were frequently associated with SCIT and also to increase the number of patients receiving allergen immunotherapy by facilitating its regular use at home. […]
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