Home > Akio Niimi, ERS 2019 – Novel P2X3 Receptor Antagonist S-600918 in Chronic Cough
Airway and Lung Infection

Akio Niimi, ERS 2019 – Novel P2X3 Receptor Antagonist S-600918 in Chronic Cough

Published Online: October 15th 2019

Akio Niimi, of Nagoya City University, Japan, spoke to us at ERS 2019 in Madrid about a study of a novel P2X3 receptor antagonist S-600918 in patients with refractory chronic cough.

Questions
1. What are the most common causes of chronic cough? (0:05)
2. What is the mechanism of action of S-600918? (0:34)
3. Could you tell us about the recent Phase II study and its findings? (1:34)
4. How does S-600918 differ from other P2X3 receptor antagonists? (2:22)
5. Which patients are most likely to respond to this treatment and in whom is it contraindicated? (2:54)

Speaker disclosures: Akio Niimi has nothing to disclose in relation to this video interview.

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Filmed at the European Respiratory Society (ERS) International Congress 2019, Madrid, Spain.

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