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Kate Clair Cruden Hughes, Amy Hai Yan Chan

Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

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As part of our Future Leaders series, we spoke with Dr Amy Wolfe, Director of the LSUHSC-Wetmore TB Clinic and Assistant Professor of Medicine at LSUHSC in New Orleans. A specialist in pulmonary and critical care medicine, Dr Wolfe shares how her early experiences in post-Katrina New Orleans inspired her focus on health equity. She discusses the challenges of treating TB in underserved communities, the importance of wraparound care, and promising innovations in pulmonology—from AI-based diagnostics to expanded access to pulmonary rehabilitation and lung cancer screening.

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Interstitial lung diseases (ILDs) are a heterogeneous group of disorders characterized by inflammation and/or fibrosis.1 Pulmonary fibrosis develops due to repeated cycles of injury and impaired repair with fibroblast activation and migration with the resultant deposition of extracellular matrix ...

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Interstitial lung disease (ILD) frequently complicates rheumatoid arthritis (RA).1 Moreover, it is more common among those who are male, smoke or are seropositive and with increasing age.1 Emergent risk factors include gain-of-function promoter variants in the MUC5B gene and ...

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Dr Paula K Skarda is a hospitalist and primary internist and works for HealthPartners and Regions Hospital in Minnesota, USA. She has been in practice for 25 years after graduating from the University of Minnesota Medical School and completing the MedPeds ...

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Mario Cazzola, Maria Gabriella Matera, Luigino Calzetta

Asthma and chronic obstructive pulmonary disease (COPD) are disorders with predominantly chronic inflammatory airway features. They are increasingly recognized as entities on a heterogeneous obstructive airway disease continuum with distinct phenotypes, various degrees of overlap, and the predominance of asthma ...

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Systemic sclerosis (SSc) is an autoimmune disorder characterized by inflammation and fibrosis of the skin and other organs. It has a range of clinical manifestations, and the typical internal organs involved include the lungs, kidneys, heart, and gastrointestinal tract. Though ...

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  Highlights Nocardiosis is has been coined “the great imitator” due to the vast heterogeneity in clinical presentation. Prevalence of disease is on the rise due to improved diagnostic techniques, as well as a growing population of immunocompromised patients, although ...

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  Highlights Diffuse alveolar hemorrhage (DAH), though rare, can be fatal and requires a high index of suspicion as frank hemoptysis may not be a presenting symptom. Multilobar pneumonia can simulate DAH both clinically and radiographically. Diagnosis relies on a ...

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Pulmonary infections caused by nontuberculous mycobacteria (NTM) are increasing in prevalence, and impose a significant health and economic burden. There are around 150 species of NTM, which are ubiquitous in the environment, and infections are transmitted by environmental spread, particularly from ...

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