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Interstitial lung diseases (ILDs) are a heterogeneous group of disorders characterized by inflammation and/or fibrosis.1 Pulmonary fibrosis develops due to repeated cycles of injury and impaired repair with fibroblast activation and migration with the resultant deposition of extracellular matrix ...
Lung cancer accounts for the highest cancer-related mortality and is the second most common cause of malignancy worldwide.1 Diagnosis at an early stage (ES) has a direct effect on management and survival rates. Overall, the 5-year survival rate from 2013 to 2019 ...
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary syndrome with a prevalence of approximately seven cases per 1 million individuals.1,2 PAP affects people of all age, sex, race and socioeconomic status. Based on the largest population studies conducted in the United ...
Welcome to the latest edition of touchREVIEWS in Respiratory & Pulmonary Diseases, which covers several hot topics in respiratory medicine, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, bronchiectasis and the ever-present subject of Coronavirus Disease 2019 (COVID-19). The ...
Lung cancer remains the leading cause of cancer-related death.1 However, five-year survival in lung cancer varies greatly based on the stage of the disease at diagnosis.2 Early lung cancer diagnosis through screening with low-dose computed tomography (CT) demonstrated a 20% reduction ...
Electronic nicotine delivery systems, colloquially referred to as e-cigarettes (ECs), or vaping products were introduced in the US market in 2007 as an alternative to cigarette smoking. They were marketed as a better alternative to nicotine replacement therapy for stopping cigarette ...
With the advent of newer drugs targeting the biochemical pathways that lead to cough, it is increasingly important to understand the definition, pathogenesis and management of this symptom. Several specialist bodies also recognize the need for guidance in this area, ...
Q. What was previously known about the risks of e-cigarette use? E-cigarettes gained rapid popularity in the US after initial release in 2007. Although they were initially marketed towards smokers as a cessation aid, their use became swiftly prevalent with younger ...
Highlights Nocardiosis is has been coined “the great imitator” due to the vast heterogeneity in clinical presentation. Prevalence of disease is on the rise due to improved diagnostic techniques, as well as a growing population of immunocompromised patients, although ...
Highlights Diffuse alveolar hemorrhage (DAH), though rare, can be fatal and requires a high index of suspicion as frank hemoptysis may not be a presenting symptom. Multilobar pneumonia can simulate DAH both clinically and radiographically. Diagnosis relies on a ...
Diffuse panbronchiolitis (DPB) is a rare inflammatory lung disease. It was first identified in 1969 and is well recognized in East Asian countries such as Japan, China, Taiwan, and Korea.1 ‘Diffuse’ and ‘pan’ words in the name indicate ‘presence of lesions ...
Assessment of peripheral pulmonary nodules and mediastinal lymph nodes is critical in the diagnosis and staging of lung cancer, which is the leading cause of cancer death worldwide.1,2 Endobronchial ultrasound (EBUS) continues to evolve, allowing clinicians the ability to evaluate ...
Professor Adcock obtained a degree in biochemistry and physiology from the University of London and later completed a PhD in pharmacology from St Thomas’s Hospital, London, on the role of nuclear receptors on sexual dimorphic patterns in the rat. ...
Sarcoidosis is a chronic systemic disease of unknown origin that is characterised by the formation of non-caseating granulomas in the affected organs, predominantly in the lungs and the intrathoracic lymph nodes.1–3 Non-caseating granulomas most often appear in the lungs and ...
Case report An eight-month-old girl presents with mild, intermittent tachypnea of several months duration. The girl’s past medical history was unremarkable except for a short neonatal intensive care unit (NICU) course secondary to respiratory distress following a term, vaginal ...
Sarcoidosis is a chronic systemic disease of unknown origin that is characterized by the formation of noncaseating granulomas in various organs, predominantly in the lungs. Granulomas are the pathologic hallmark of the disease and usually occur in the bronchial submucosa ...
Airway inflammatory diseases are assessed and managed via multiple measurements, including airway caliber, airway responsiveness, and airway inflammation. Exacerbations post diagnosis is also a critical marker in terms of disease status and progression. Currently, diagnosis and monitoring of asthma1 and ...
Tube thoracostomy (chest tube placement) is a common procedure used in pathologic conditions to drain the pleural space of air (pneumothorax), blood (hemothorax), serum (pleural effusion), lymph (chylothorax), pus (empyema), or a combination of these.1 In these instances, when an ...
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