An Introduction to Paediatrics
A number of respiratory conditions largely affect the paediatric patient, including cystic fibrosis, asthma and allergy. Recent research into genetic drivers has revolutionized the treatment of cystic fibrosis, with new and effective targeted therapies available and undergoing further research. In asthma, treatments such as inhaled corticosteroids are well established, but research into innovative therapies is ongoing.
Browse our selection of video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and a selection of peer-reviewed articles from the journal portfolio.
Robin Deterding, ERS 2022: Findings from the InPedILD Trial
The InPedILD trial was a phase 3, double-blind placebo-controlled trial investigating nintedanib in children and adolescents with fibrosing interstitial lung diseases (ClinicalTrials.gov: NCT04093024). We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) to discuss the aims, design, eligibility criteria and findings from the phase 3 study. […]
Robin Deterding, ERS 2022: Nintedanib for Children and Adolescents with Fibrosing Interstitial Lung Diseases
Nintedanib is an inhibitor of tyrosine kinases involved in the progression of pulmonary fibrosis and blocks the signalling pathways involved in fibrotic processes. We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) around the incidence, prognosis and unmet needs in the treatment of childhood interstitial lung […]
Identifying, diagnosing and treating patients with later-onset SMA
Dr Julie Parsons reviews the diagnosis and approved treatments for later-onset SMA, highlighting their impact on the natural history of SMA.
- Recall possible symptoms of SMA in adolescent and adult patients and relevant differential diagnostic tests
- Appraise the role of current and future treatment approaches for improving outcomes in patients with older-onset SMA
- Evaluate how the natural history of SMA is evolving with the use of disease-modifying therapies
Maintaining quality of life in patients with later-onset SMA: The patient journey from diagnosis to management
Watch members of the MDT and two patients discuss the diagnosis and management of SMA in adolescents and adults.
- Recall the typical clinical presentation of patients with milder SMA phenotypes and the processes for differential diagnosis
- Discuss patient needs as they transition from paediatric to adult healthcare services
- Formulate processes for the provision of multidisciplinary care to adolescent and adult patients with SMA
Nirsevimab: An Extended Half-life Monoclonal Antibody for the Prevention of Infant Respiratory Syncytial Virus Infection
touchREVIEWS in Respiratory & Pulmonary Medicine. 2021;6(1):38–41 DOI: https://doi.org/10.17925/USPRD.2021.6.1.38
Respiratory syncytial virus (RSV) is a ubiquitous virus that causes annual epidemics of infection in young children in all parts of the world. In temperate regions, epidemics are seasonal, and predictable during the winter months. Approximately half of all infants develop their first RSV infection prior to their first birthday. By 24 months of age, […]
Refika Ersu, ERS 2018 – Paediatric physiology and sleep at ERS: what is new?
Editorial board member and new Chair Elect of the Paediatric Respiratory Physiology and Sleep Section of the ERS Paediatric Assembly Refika Ersu (Marmara University, Istanbul, Turkey) chats to us about unmet needs and exciting advances in respiratory and sleep physiology in children. Questions 1. What are the major unmet needs in paediatric sleep medicine? (0:12) […]
Fabio Midulla, ERS 2018 – Acute viral bronchiolitis
Editorial board member Fabio Midulla (Sapienza University, Rome, Italy) chats to us about acute viral bronchiolitis, including risk factors, challenges managing the condition, risks and recent advances. Questions 1. What are the major risk factors for acute viral bronchiolitis? (0:12) 2. What are the challenges in the management of acute viral bronchiolitis? (1:02) 3. What […]
Updates in the Guidelines and Treatment of Ventilator-dependent Children
US Respiratory & Pulmonary Diseases. 2018;3(1):19–21 DOI: https://doi.org/10.17925/USRPD.2018.3.1.19
My experience in the care of ventilator-dependent children involves over 20 years’ experience in both the home and long-term care environments. I have managed over 50 ventilator-dependent children in a university-based practice and have weaned at least two children per year completely off mechanical ventilation. In addition, I have helped in the development of […]
Inducible Laryngeal Obstruction in the Paediatric Population – Review of the Literature and Current Understanding
European Respiratory & Pulmonary Diseases. 2018;4(1):45–8 DOI: https://doi.org/10.17925/ERPD.2018.4.1.45
Inducible laryngeal obstruction (ILO), previously designated as vocal cord dysfunction (VCD), is characterised by a transient and reversible narrowing of the larynx in response to external triggers, resulting in symptoms such as cough, dyspnoea and noisy breathing.1,2 Adduction of the vocal folds usually occurs in inhalation but can also happen in exhalation, restricting movement of […]
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