An Introduction to Airway Disease
The incidence of respiratory allergies is increasing, particularly in industrialized areas. Allergic inflammation can occur in both the upper and lower airways, and can differ substantially in intensity. Traditional drug therapy such as antihistamines, corticosteroids, anticholinergic agents and leukotriene inhibitors is important in reducing and preventing symptoms and is essential in acute use. More recent therapies including anti-immunoglobin E (IgE) therapy, anti-interleukin (IL) monoclonal antibodies, and phosphodiesterase 4/phospholipaseA2 inhibitors, have improved outcomes. However, in order to develop more effective therapies, further research is needed into the molecular mechanisms underlying respiratory allergy onset, particularly in terms of intracellular reactions and the cytosolic Ca2+ balance.
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Airway Disease Content
Management of patients with NTM-LD: Improving adherence for optimal outcomes
Watch expert pulmonologists discuss how to optimize the diagnosis and management of patients with NTM-LD
- Appraise strategies to reduce time to diagnosis for patients with NTM-LD
- Utilize guideline recommendations when setting individualized treatment goals for patients with NTM-LD
- Apply strategies to manage adverse events for improved outcomes and adherence in patients with NTM-LD
Minimizing the clinical burden of chronic rhinosinusitis with nasal polyposis
Watch ENT specialists discuss key considerations in optimizing the management of patients with CRSwNP.
- Describe the burden of disease of CRSwNP and the importance of early diagnosis
- Explain the pathophysiology of CRSwNP and how this can guide treatment decisions
- Summarize the clinical evidence supporting the use of current and emerging treatment options for CRSwNP
Strategies for the management of severe type 2 asthma: Expert insight into optimizing care
MDT specialists, plus a patient with severe asthma, discuss the disease burden and the role of biologics in the long-term management of severe T2 asthma
- Recognize the challenges associated with living with severe asthma
- Discuss the role of biomarkers in guiding biologic treatment selection for patients with severe T2 asthma
- Recall evidence-based guidance on the long-term management of patients with severe T2 asthma
Foreword touchREVIEWS in Respiratory & Pulmonary Diseases Volume 6, Issue 1, 2021
Welcome to the latest issue of touchREVIEWS in Respiratory & Pulmonary Diseases. The past three years have been intensely busy, chaotic and traumatic, especially for those of us working in the respiratory field. Having personally spent hundreds of hours only working in COVID-19-related critical care, I have missed out on many new developments in respiratory healthcare. […]
Unravelling endotypes for treatment selection in severe type 2 asthma
Experts discuss how endotyping and biomarkers can help to guide optimal treatment selection in patients severe type 2 asthma
- Recall key data on the serious consequences of severe type 2 asthma
- Summarize severe asthma endotypes and the corresponding selection of biological therapies
- Evaluate the most recent evidence on key aspects of long-term management of patients with severe type 2 asthma
New guideline-based strategies for improving outcomes in patients with NTM-LD
Watch leading experts provide advice on how clinicians should manage their patients with NTM-LD within the context of recently updated guidelines.
- Identify the clinical presentations associated with NTM-LD which can help reduce time to diagnosis and initiation of treatment
- Apply guideline-based treatment options to set individualized treatment goals in collaboration with patients with NTM-LD
- Evaluate strategies to improve adherence and manage adverse events in patients with NTM-LD
Strategies for the management of chronic rhinosinusitis with nasal polyps: Expert insight in optimizing care
Watch a panel of experts discuss challenges in the diagnosis of CRSwNP and considerations for optimal management of the disease.
- Define diagnostic criteria for CRSwNP
- Recognize that eosinophilic inflammation in CRSwNP is a predictor of disease recurrence
- Outline advancements in the treatment of CRSwNP
Eosinophilic inflammatory diseases of the respiratory system: New therapeutic options
Watch a panel of experts discuss how to identify and manage patients with inflammatory respiratory diseases, with a focus on severe eosinophilic asthma.
- Recognize the role of eosinophils and type 2 inflammation in respiratory disease
- Understand the diagnostic methods used to differentiate inflammatory diseases of the respiratory system
- Recall disease states that may benefit from therapies that target the complex interaction between eosinophils and their environment
The role of eosinophils in physiology and disease: Is complete depletion of eosinophils the goal?
Watch Dr Enrico Heffler describe how eosinophilic inflammation can be targeted for the treatment of inflammatory respiratory diseases.
- Understand the dynamics of eosinophils across the human body in wellness and disease
- Discuss clinical scenarios in which eosinophilic therapy may be beneficial
- Recognize how new eosinophilic therapies offer promise for the future treatment of eosinophil-mediated diseases
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