Welcome to this year's edition of US Respiratory & Pulmonary Diseases introduced by Editorial Board member Robert Balk. Expert interviews with Don Sin, Juzar Ali, and Ronald Morton touch on the relationship of telomere length of leukocytes and clinical outcomes in individuals with chronic obstructive pulmonary disease (COPD), risk factors for and management of nontuberculous mycobacterial pulmonary infections, and recent updates in the American Thoracic Society and Canadian Thoracic Society clinical guidelines for pediatric home mechanical ventilation, respectively. In editorials, we have a thought-provoking discussion around the dissemination and relevance of medical literature and how this may change in the future (Kaszuba and Alberts), and two important calls to action around the high prevalence of undiagnosed asthma in shelters in conflict zones, and the increasing popularity of waterpipe tobacco smoking (Mohammad). In a review article, Eric Gartman describes the normal changes that occur during sleep, how these are affected in patients with neuromuscular and chest wall disorders, and how to assess patients with neuromuscular disease for the presence of sleep disorders. Finally, Adan Mora presents a case of diffuse pulmonary hemorrhage. Recognition of this rare but fatal condition is important as it may be misdiagnosed as multilobar pneumonia, but its diagnostic workup and treatment is different. Across the various articles, we hope there's something of clinical relevance for you to enjoy. We are now accepting submissions for our 2019 edition and welcome enquires through our submission site here.