Welcome to the autumn edition of the European Respiratory & Pulmonary Diseases, Editorial Board member Fabio Midulla gives an excellent introduction to the edition and highlights the key articles. This edition includes a range of editorials, reviews and case reports for you to read and enjoy.This edition begins with a number of topical editorials, succinctly examining a range of important topics including cystic fibrosis, pulmonary arterial hypertension and obstructive sleep apnoea. We also include an interesting review by Loebinger and Welte, which discusses the unmet needs and latest advances in the diagnosis and treatment of nontuberculous mycobacterial pulmonary disease.We hope you enjoy this edition of the European Respiratory & Pulmonary Diseases and that it provides a useful information relevant to your practice and interests. We are currently accepting submissions and welcome enquires through our submission form here.
Foreword – European Respiratory & Pulmonary Diseases, 2016;2(2):47
Welcome to the latest edition of European Respiratory & Pulmonary Diseases, which features a wide range of topical reviews and editorials. This issue begins with a discussion by Griesenbach and Alton of gene therapy in cystic fibrosis, a subject that has recently experienced a resurgence in interest within the medical community. Pulmonary arterial hypertension (PAH) […]
Cystic Fibrosis Gene Therapy – Not Low-hanging Fruit
Cystic fibrosis (CF) is caused by mutations in a single gene; treatment burden is high and life expectancy is significantly shortened (median age of survival in the UK is ~40 years). Although CF is a multi-organ disease, chronic lung infection and inflammation are the biggest causes of morbidity and mortality in the developed world. Identification […]
Pulmonary Arterial Hypertension Management – A New Approach For a Rare Disease
Pulmonary arterial hypertension (PAH) is a rare, deadly and incurable condition.1 With a five-year survival rate below 60%, the outcome of this disease is not any better than that of many cancers.1,2 However, numerous treatment options are currently available: more than 20 randomised controlled trials (RCTs) have been conducted over the past 10 years, allowing […]
Sleep Disordered Breathing in Children
Breathing problems during sleep commonly occur in children. Obstructive sleep apnoea (OSA) is the most common breathing-related problem that occurs during sleep and snoring is the main symptom. Habitual snoring, which is defined as snoring for more than three days a week, is seen in 7.45% of children.1 OSA is defined as recurrent events of […]
Current Perspectives in the Diagnosis and Treatment of Nontuberculous Mycobacterial Pulmonary Disease
Nontuberculous mycobacteria (NTM) are a diverse group of bacteria with a wide spectrum of virulence.1 They are a microaerobic, non-motile organisms that have a lipid-rich, hydrophobic cell wall that is substantially thicker compared with most other bacteria.2 NTM are associated with biofilm formation, which contributes to disinfectant- and antibiotic-resistance.3–5 Many of these organisms are also […]
Sarcomatoid Carcinoma of the Lung Mimicking a Thromboembolic Disease
Primary lung carcinoma spreading to pulmonary vessels and presenting as a thromboembolic disease is quite rare and only few individual cases have been reported in the English literature.1-3 The prognostic significance of pulmonary vessel invasion by lung carcinoma is unclear and the treatment is challenging. We aim to describe an unusual case of sarcomatoid carcinoma […]
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