Articles
A Novel Therapeutic Target in Asthma - The A2B Adenosine Receptor
The observation that adenosine-mediated BHR is reduced but persistent in mast-cell-deficient mice supports the existence of a mast-cell-independent...
A woman with cystic fibrosis, severe hypoxaemia, an atrial thrombus and a patent foramen ovale: a case report
Introduction Cystic fibrosis (CF) is an autosomal, recessively inherited disease caused by mutations in the cystic fibrosis transmembrane...
Acute Respiratory Distress Syndrome Acquired Brain Injury An Under-recognized and Debilitating Condition
Research is limited regarding cognitive outcomes in survivors of ARDS; however, these patients are at risk for delirium (e.g. acute cerebral...
Advances in Antimicrobial Therapy of Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis
Antimicrobial therapy has made an important contribution to increasing the life expectancy of CF patients and is one of the cornerstones of the...
Advantages and Disadvantages of Medical Therapies for Smoking Cessation
Smoking cessation rates are boosted with behavioural therapy, drugs and motivational support provided by a health professional. Three medical...
Adverse Effects of Anti-tuberculosis Chemotherapy
There is also an opposing view that most patients with TB complete their treatment without serious adverse effects.2 In addition, the frequency of...
Airway Diseases - Influential Developments in the Last Five Years
.text1 { font-family: verdana; font-size: 14px; font-weight: bold; color: 339966; }There have been major...
Airway Inflammation in Asthma Non-invasive Assessment in Clinical Practice
Airway inflammation is probably the most important component of asthma. In spite of that, monitoring of disease activity in asthma often relies on a...
Airway Pressure Release Ventilation in Pediatrics
Theory APRV was first described by Downs and Stock in 1987. This form of ventilation consists of continuous positive airway pressure (CPAP) with...
Allergic Rhinitis and Asthma - Systemic Condition or Local Disease?
Local allergen exposure at one end of the respiratory system induces mucosal inflammation at the other end, and vice versa. Therefore, upper and...
Alpha-1 Antitrypsin Deficiency and the Genetics of Chronic Obstructive Pulmonary Disease
AAT is a circulating protein, synthesized primarily in the liver, with potent antiprotease and anti-inflammatory activities. While more than 100...
Amantadine, oseltamivir and zanamivir for the treatment of influenza
DISEASE/CONDITION(S) Influenza Note: This guidance does not cover the circumstances of a pandemic, impending pandemic or a widespread epidemic of a...
Antibiotic Efficacy in Respiratory Tract Infections - Application of Pharmacokinetic and Pharmacodynamic Principles
While most respiratory infections are viral in origin, primary and secondary bacterial infections are the reasons why antibiotics are prescribed, as...
Applying the Asthma Guidelines to Patients - Barriers and Current State
Annual healthcare costs due to asthma has been estimated to be US$12.7 billion per year with lost productivity estimated to be US$4.6 billion.2 ...
As Use of Herbal Remedies Soars, Patients Taking These and Cardiovascular Medications May be at Heightened Risk of Dangerous, Potentially Life-Threatening Interactions
"Many people have a false sense of security about these herbal products because they are seen as 'natural,'" said Arshad Jahangir, M.D.,...
Asthma Disease Management
In 1991, in response to observed increasing asthma mortality in the 1970s and 1980s, especially among inner-city African-Americans, the National...
Asthma in the Elderly
This is a cardinal feature of asthma at any age. There is a common misperception that asthma is predominantly a childhood disease. However, in a...
Asthma Management
The actions that doctors and patients need to take in order to successfully manage and control asthma are to: • avoid exposure to triggering...
Asthma Pharmacotherapy
Pharmacotherapy of asthma is unique in several ways. First, asthma is characterized by airway inflammation, bronchial hyperresponsiveness and...
