Pulmonary fibrosis secondary to siderosis causing symptomatic respiratory disease: a case report
Pulmonary fibrosis secondary to siderosis causing symptomatic respiratory disease: a case report
Published: December 2009
Nevertheless, symptomatic disease with interstitial fibrosis has been described in arc welders [4]. Some authors have postulated that these rare cases are secondary to concomitant inhalation of silicates or asbestos that can occur in many occupations associated with exposure to iron [4]. However, Funahashi et al. challenged this view after investigating 10 symptomatic welders and performing energy dispersive X-ray analysis on lung tissue for elemental content [5]. Despite demonstrating restrictive defects in seven of their patients, and mild to moderate airway obstruction in a further two, they found no difference between the pulmonary silicon content of patients with symptomatic 'welders' pneumoconiosis' and that of age-matched control lungs [5]. Some degree of parenchymal fibrosis was present in all patients, and in 50%, this fibrosis was considered moderate to marked. As many of the iron-containing particles were seen in fibrotic alveolar septa, it was postulated that the fibrosis was a reaction to these particles rather than the co-existing silicosis [5].
Conclusion
Our report illustrates that symptomatic respiratory disease due to mild peribronchiolar fibrosis can occur with pulmonary siderosis despite wearing a mask. Furthermore, it reinforces the need to compile a detailed occupational history in individuals with respiratory disease. It is particularly important to obtain an accurate diagnosis of interstitial shadowing on chest radiograph as pulmonary siderosis in our patient had a relatively good prognosis compared with other interstitial and small airway disorders.
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- Billings CG, Howard P: Occupational siderosis and welders' lung: a review. Monaldi Arch Chest Dis 1993, 48:304-314.
- Doig AT, McLaughlin AIG: Clearing of X-ray shadows in welders' siderosis. Lancet 1948, 1:789-791.
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- Funahashi A, Schlueter DP, Pintar K, Bemis EL, Siegesmund KA: Welders' pneumoconiosis: tissue elemental microanalysis by energy dispersive X-ray analysis. Br J Ind Med 1988, 45:14-18.
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