Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report
Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report
Journal of Medical Case Reports 2008, 2:384
Published: January 2010
Published: January 2010
Abstract
Introduction
There are increasing reports of bowel cancer in cystic fibrosis, suggesting a possible causal link. Individuals with cystic fibrosis who have advanced lung disease present a high operative risk, limiting curative treatment options in early bowel malignancy.
We describe a 41-year-old Caucasian woman with cystic fibrosis and severe lung disease who had been considered for lung transplantation, who presented with rectal bleeding and was found to have a Stage I adenocarcinoma of the sigmoid colon. After considerable discussion as to the operative risks, she underwent a laparoscopic resection and remains relatively well 1 year postoperatively with no ecurrence.
Conclusion
We discuss the complexity of the management decisions for cystic fibrosis patients with severe lung disease and early stage colonic malignancy, particularly in the context of potential need for lung transplantation. The case demonstrates that cystic fibrosis patients with very severe lung function impairment may undergo laparoscopic abdominal surgical interventions without compromising postoperative airway clearance.
Keywords:
cystic fibrosis, cystic fibrosis treatment, sign symptoms cystic fibrosis, cystic fibrosis gene therapy, cystic fibrosis inherited, cystic fibrosis pulmonary guidelines, cystic fibrosis lung infections,
cystic fibrosis, cystic fibrosis treatment, sign symptoms cystic fibrosis, cystic fibrosis gene therapy, cystic fibrosis inherited, cystic fibrosis pulmonary guidelines, cystic fibrosis lung infections,
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